+4 or trisomy 4

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Trisomy 4 Identifies a Subset of Acute Nonlymphocytic

C YTOGENETIC studies have shown that some acquired chromosomal abnormalities are characteristically associated with morphobogically defined types of acute nonlymphocytic leukemia (ANLL). For example, a t(8;21) is typicabby associated with an M2 leukemia with granulated myeboblasts’; a t(lS;l7) is specific for both the granular and the hypogranubar form of the promyelocytic M3 leukemia2’3; a str...

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Trisomy 4 identifies a subset of acute nonlymphocytic leukemias.

We present four patients with acute nonlymphocytic leukemia, one M2 and three M4 French-American-British (FAB) types and one patient with refractory anemia with excess of blasts in transformation who at diagnosis had trisomy of chromosome 4 as the primary karyotypic anomaly. This chromosome anomaly probably defines a previously undescribed subset of acute nonlymphoid leukemias. Hematologic char...

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+ 5 or trisomy 5

In childhood ALL, an extra chromosome 5 is commonly encountered in cases with hyperdiploidy >50 chromosomes. The presence of trisomy 5 in high hyperdiploid childhood ALL is associated with a less favourable clinical outcome. Trisomy 5 as a sole abnormality in ALL is exceedingly rare and described in only 3 cases, including 2 adult ALL and 1 paediatrics case occurring in a 12-year old girl. Tris...

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+ 12 or trisomy 12

Phenotype/cell stem origin virgin CD5+ recirculating B-cell; the classical CLL phenotype is CD5+, CD23+, CD22-, CD79a-, FMC7-, sIg weak; trisomy 12 is more often observed in CLL with morphologically and immunologically atypical cells, displaying CD5 negativity or FMC7 positivity and strong surface immunoglobulin staining; trisomy 12 is present in proliferating cells and seems to be associated w...

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4 Split - or - Steal Game

1 Subject Matter of the Course Game theory is the theory of competitions. It is based on the premise that the competitors act selfishly and rationally. In many applications, it is important to understand or even predict the behavior of selfish players and the outcomes of competitions. Game theory is a mathematical field and particularly used in economics, science, and engineering. Computer scie...

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ژورنال

عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology

سال: 2011

ISSN: 1768-3262

DOI: 10.4267/2042/37648